Progressive Resistance Exercise in Rheumatoid Arthritis

Progressive Resistance Exercise in Rheumatoid Arthritis Patients: a Randomized Controlled Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02219022

Enrollment

Registered

2014-08-18

Start date

2011-07-31

Completion date

2015-10-31

Last updated

2016-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rheumatoid Arthritis

Keywords

Rheumatoid arthritis, Progressive resistance exercise, Pain, Functional capacity, Quality of life, Muscle strength

Brief summary

A randomized controlled trial with rheumatoid arthritis patients will be realized. Patients will be randomized into two groups. Experimental group will do a 12 weeks training of progressive resistance exercise for global muscles and remain with the clinical treatment and the control only remain with the clinical treatment. Patients will be evaluated at baseline, after 6, 12 and 24 weeks.

Interventions

OTHERControl group

OTHERExperimental group

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Rheumatoid arthritis according to American College of Rheumatology 2010 * Both genders * Age between 18 and 65 years * Functional class I, II and III * Stable medication within the three months preceding the study * Haven't done any kind of regular exercise (two or more times per Week) for at least three months before study start * Have agreed to participate in the study and signed an informed consent form.

Exclusion criteria

* Participating in another type of study * Have difficulty understanding the evaluation tools with fibromyalgia * Joint deformities that make impossible do the exercises * Other musculoskeletal diseases * Other diseases that contraindicate exercises.

Design outcomes

Primary

Measure	Time frame
Change in pain - Visual analogue scale	baseline, 6, 12 and 24 weeks

Secondary

Measure	Time frame
Change in function capacity - Health Assessment questionaire	Baseline, after 6, 12 and 24 weeks
Change in quality of life - Short form 36	baseline, after 6, 12 and 24 weeks
Change in strength - 1 maximum repetition	baseline, after 6, 12 and 24 weeks

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026