Bone Structure in Patients With Adult Onset Growth Hormone Deficiency Assessed Using High Resolution Peripheral Quantitative Computed Tomography

Bone Geometry, Volumetric Density, Microarchitecture and Estimated Bone Strength Assessed by High Resolution Peripheral Quantitative Computed Tomography in Patients With Adult Onset Growth Hormone Deficiency

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02218710

Enrollment

Registered

2014-08-18

Start date

2014-09-30

Completion date

2019-06-30

Last updated

2025-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult Onset Growth Hormone Deficiency

Brief summary

The aim of the study is to assess bone geometry, bone compartment specific volumetric densities and micro-architecture as well as to evaluate non-invasive estimates of bone strength in patients with adult onset growth hormone deficiency.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Men and women diagnosed with Adult onset Growth Hormone Deficiency * Age between 18-80 * Informed consent

Exclusion criteria

* Competing bone disease (e.g.. Mb. Paget, myelomatosis, osteogenesis imperfecta, osteoporosis, primary hyperparathyroidism) * Ongoing medical treatment affecting bone metabolism (eg. osteoporosis medications) * Ongoing pregnancy or breast feeding

Design outcomes

Primary

Measure	Time frame
volumetric bone mineral density in grams per cc	1 year

Countries

Denmark

Outcome results