Carriage of Bordetella Pertussis
Conditions
Keywords
Bordetella pertussis, Carriage rates in young adults
Brief summary
The objective in this observational cohort study of young adults sampled at three intervals during the academic year is to ascertain if there is carriage of B. pertussis in asymptomatic individuals. We hypothesize that in asymptomatic college students there is no carriage of B. pertussis detectable by polymerase chain reaction (PCR) assay.
Interventions
None listed
Sponsors
University of Virginia
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Age 18 and above * Not immunosuppressed * Not HIV positive (not known to be/self-reported) * Able to tolerate swab procedures * Able to provide consent
Exclusion criteria
* No antimicrobial or immunosuppressive medications taken for chronic conditions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with B. pertussis by PCR in nasopharyngeal sample at first timepoint | 30 minutes | Participants will be tested for B. pertussis by PCR at one visit in October 2014, 30 minutes. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with B. pertussis by PCR in nasopharyngeal sample at second timepoint | 30 minutes | Participants will be tested for B. pertussis by PCR at one visit in January 2015, 30 minutes. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with B. pertussis by PCR in nasopharyngeal sample at third timepoint | 30 minutes | Participants will be tested for B. pertussis by PCR at one visit in April 2015, 30 minutes. |
Countries
United States
Outcome results
None listed