Intraocular Pressure Changes During Tracheal Extubation
Conditions
Keywords
two reversal methods, changes in IOP, heart rate, blood pressure, tracheal extubation
Brief summary
The aim of this study, comparison of effects of sugammadex versus neostigmine/atropine combination on hemodynamic parameters and intraocular pressure during tracheal extubation. This prospective, randomised study was designed to compare two reversal methods with respect to changes in IOP, heart rate and blood pressure during tracheal extubation period.
Interventions
DRUGsugammadex
sugammadex 2 mg/kg
neostigmine 0,05 mg/kg + atropine 0,025 mg/kg
Sponsors
Ordu University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* ASA I-II physical status * elective surgery * endotracheal intubation under general anesthesia
Exclusion criteria
* emergency surgery * pregnancy * laparoscopic surgery * prone position * BMI \> 30 kg/m2 * sedative drug use in last month * patients with glaucoma. * ASA \> II physical status
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraocular pressure | baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation |
Secondary
| Measure | Time frame |
|---|---|
| heart rate | baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation |
| blood pressure | baseline, before applying reversal agent, after applying reversal agent, one, three, five and ten minutes after tracheal extubation |
Countries
Turkey (Türkiye)
Outcome results
None listed