Retinal Vessel Diameter in Branch Retinal Vein Occlusion

Change of Retinal Vessel Diameter in Branch Retinal Vein Occlusion After Intravitreal Bevacizumab Injection

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02215109

Enrollment

Registered

2014-08-13

Start date

2012-04-30

Completion date

2016-08-31

Last updated

2016-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Branch Retinal Vein Occlusion

Brief summary

The authors investigated the consecutive change of retinal vessel's diameter in affected eye and fellow eye of Branch Retinal Vein Occlusion.

Detailed description

Twenty five consecutive patients who had undergone intravitreal bevacizumab injection for Branch Retinal Vein Occlusion with macular edema were included in this study. All subjects were enrolled between April, 2012 and April, 2013 in the Department of Ophthalmology, Kyungpook National University Hospital.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 85 Years

Healthy volunteers

Inclusion criteria

* Best-corrected visual acuity less than 20/40 * Central subfield macular thickness (CSMT) 300 μm or greater on spectral-domain optical coherence tomography

Exclusion criteria

* Patients with recurrent BRVO * History of previous treatments for BRVO including vitreoretinal surgery, intravitreal injection, subtenon injection or laser photocoagulation * Patients with diabetes or dyslipidemia * IOP ≥ 22mmHg, treatment for glaucoma, a family history of glaucoma, or optic neuropathy * High myopia (\<-6 Diopters), high hyperopia (\>6 Diopters) or a history of refractive surgeries * Co-existing retinal disease other than BRVO * Corneal diseases include ulcer, keratoconus and a history of corneal laceration * Cataract and other media opacities resulting in visual impairment or poor fundus images

Design outcomes

Primary

Measure	Time frame	Description
Unoccluded retinal vessel diameter of Branch Retinal Vein Occlusion	0, 1, 3, and 6 months	To evaluate the change of unoccluded retinal vessel diameter in affected eye of Branch Retinal Vein Occlusion and unaffected fellow eye.

Countries

South Korea

Outcome results