Effect of Chrysanthemum Flower Oil and Its Dose-dependency on Hyperuricemia

A Randomized, Double-blind, Parallel Group Study to Evaluate the Effect of Chrysanthemum Flower Oil and Its Dose-dependency in Subjects With Hyperuricemia

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02213562

Enrollment

Registered

2014-08-11

Start date

2014-07-31

Completion date

2016-03-31

Last updated

2016-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperuricemia

Brief summary

The aim of this study is to investigate the efficacy and dose-dependency of chrysanthemum flower oil in suppressing serum uric acid.

Interventions

DIETARY_SUPPLEMENT200 mg of chrysanthemum flower oil

DIETARY_SUPPLEMENT300 mg of chrysanthemum flower oil

DIETARY_SUPPLEMENT400 mg of chrysanthemum flower oil

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

MALE

Age

30 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Serum uric acid 6.8-8.9 mg/dL

Exclusion criteria

* Taking anti-hyperuricemic drugs * History of gouty attack * Taking drugs or functional food that may affect serum uric acid level * Hypertention, hyperlipidemia, or diabetes millitus * Participation in any clinical trial within 90 days of the commencement of the trial * Renal or hepatic dysfunction * Heart disease * History of severe disease and/or major surgery

Design outcomes

Primary

Measure	Time frame
Change in serum uric acid from baseline	Every 4 weeks (Overall 8 weeks)
Change in uric acid clearance from baseline	Every 4 weeks (Overall 8 weeks)

Countries

Japan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026