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Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40 in Vitrectomy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02212340
Enrollment
84
Registered
2014-08-08
Start date
2014-07-31
Completion date
2016-03-31
Last updated
2016-09-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitrectomy Operation Under General Anesthesia

Keywords

propofol, desflurane, quality of recovery, vitrectomy

Brief summary

Total intravenous anesthesia (TIVA) and inhalation anesthesia are both widely and safely used, and there are many clinical trials comparing these on various aspects of anesthesia. However, there have not been studies comparing the quality of recovery from the different methods of general anesthesia in vitrectomy. In this study, the investigators compare the functional recovery after general anesthesia in TIVA and inhalation anesthesia with QoR-40 questionnaire in vitrectomy.

Interventions

DRUGfresofol and remifentanil

Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

Anesthesia is maintained with fresofol and remifentanil in TIVA group or with desflurane and remifentanil in Des group according to randomly allocated group.

Sponsors

Yonsei University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

1. Patients (20-80 years old) scheduled for vitrectomy surgery undergoing general anesthesia. 2. ASA 1-3

Exclusion criteria

1. Patients with allergy to anesthetic agents 2. Anticipated difficult airway 3. BMI \> 30 kg/m2 4. Chronic obstructive pulmonary disease 5. Heart failure 6. Unstable angina

Design outcomes

Primary

MeasureTime frame
QoR-40 scoreat 6 hours later after surgery

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026