Cardiovascular Diseases
Conditions
Keywords
prevention, cardiovascular disease, risk factors
Brief summary
To evaluate long-term effects of one individual- and population-oriented cardiovascular prevention programs in primary care.
Detailed description
In Sweden there are unique opportunities to create a relevant comparison group for this study, which is of great importance to the value of this cohort study. Of the three study populations two (2-3)will be created by using national registries. 1. The screened group consists of the individuals (n = 5938) who had direct contact with the prevention program, ie undergone a voluntary opportunistic cardiovascular screening (questionnaire, physical examination and testing in connection with visits to health centers) and the rest of all individuals who lived in Sollentuna Municipality between 1988-1993. 2. Relatives of individuals included in the screened group who lived in Stockholm county at the time of the intervention will be identified by the use of the Medical Birth Register and the Multi-Generation Register. Family members are defined as parents, siblings and children and husband / wife to those in thescreened group and will be analyzed in the same way as those who participated in the intervention for risk of developing cardiovascular disease and cancer. 3. The comparison group consists of the entire population of Stockholm County minus Sollentuna 1988-93, taking into account population changes (migration, birth, death) during the period. This three populations will be followed-up in national registries and databases All subjects will be monitored for example disease history, socio-economics and biochemical risk factors presented below national registries and research databases. When all the matches of national registers and a local register (AMORIS)have been done the database will de-identified and anonymized data to be available for statistical processing.
Interventions
None listed
Sponsors
Swedish Heart Lung Foundation
Karolinska Institutet
Study design
Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
in the risk intervention group: * Individuals 15 years of age or more who visited three (four) health care centres in Sollentuna 1988-1993 were offered to participate in the prevention program
Exclusion criteria
in the screened intervention group: * Age \< 15 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence and mortality in acute myocardial infarction, stroke, cardiovascular disease, and overall mortality, a twenty year follow-up of a prevention program. | 24 years | Long term follow-up of a cardiovascular prevention program by using Swedish national patient registries |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| A follow-up of drug treatment of diabetes, dyslipidemia and hypertension | 24 years | By using the drug register in Sweden do a follow-up of drug treatment in the cohort |
Other
| Measure | Time frame | Description |
|---|---|---|
| Incidence and mortality in cancer | 24 years | Incidence and mortality in cancer - a twenty year follow-up by using the swedish cancer register |
| Consumption of medical care overall and for different diagnostic groups | 24 years | To study medical care consumption overall for different diagnostic groups by using different registers in Sweden |
| Health economic aspects | 24 years | Health economic aspects such as 1. health care consumption in total and for different diagnostic groups 2. care costs 3. impact on indirect costs (lost working years and sick leave) 4. intervention cost will be studied |
| Time trends of morbidity and mortality in acute myocardial infarction, stroke, cardiovascular disease and total mortality | 24 years | To study time trends of morbidity and mortality in acute myocardial infarction, stroke, cardiovascular disease and total mortality by use of National Swedish registries. |
Outcome results
None listed