A Trial on Treatments of Hirschsprung Allied Disease

A Prospective, Randomized Controlled Trial of Conservative Versus Surgery Treatment of Children With Hirschsprung Allied Disease

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02212054

Enrollment

Registered

2014-08-08

Start date

2020-05-01

Completion date

2025-12-01

Last updated

2020-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications of Treatment, Complication of Surgical Procedure, Megacolon, Not Hirschsprung

Brief summary

The present study was designed to compare the efficacy of conservative treatment to operative treatment for improvement of constipation symptoms in children with Hirschsprung allied disease

Detailed description

The present study was designed to compare the efficacy of conservative treatment,such as anal dilatation, colonic lavage and so on, to operative treatment for improvement of constipation symptoms in children with Hirschsprung allied disease

Interventions

BEHAVIORALconservative

anal dilatation; colonic lavage; oral probiotic

PROCEDUREoperative

one stage pull through radical colectomy

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

1 Years to 14 Years

Healthy volunteers

Inclusion criteria

* hard or firm stools for twice or less per week * a predicting score of less than 5 refer to literature: Wu, X.J., et al., A new diagnostic scoring system to differentiate Hirschsprung's disease from Hirschsprung's disease-allied disorders in patients with suspected intestinal dysganglionosis. Int J Colorectal Dis, 2013. 28(5): p. 689-96

Exclusion criteria

* functional constipation * a predicting score of more than 5 refer to literature: Wu, X.J., et al., A new diagnostic scoring system to differentiate Hirschsprung's disease from Hirschsprung's disease-allied disorders in patients with suspected intestinal dysganglionosis. Int J Colorectal Dis, 2013. 28(5): p. 689-96

Design outcomes

Primary

Measure	Time frame	Description
the change of defecation frequency	6~12 months	the changes of defecation frequency at 6\ 12 months after treatment

Secondary

Measure	Time frame	Description
stool pattern	6~12 months	stool pattern as hard stool or loose stool
controlling stool ability	6~12 months	whether patients' controlling stool ability is better or not after treatment
complications	6~12 months	complications were suffered by patients or not

Countries

China

Contacts

Primary ContactXiong J Feng, MD,PhD

31699788@qq.com0086-27-83665309

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026