Dry Eye
Conditions
Keywords
Transepithelial PRK, Dry eye, Schirmer test, Tear break up time, Dry eye after advanced surface ablation technique
Brief summary
The aim of the study is to evaluate the severity of dry eye syndrome following excimer laser vision correction using no-touch all-laser photorefractive keratectomy in comparison to conventional lasik
Detailed description
Prospective interventional clinical study 2 groups: Group A : 20 eyes of 10 patients undergoing transepithelial PRK Group B: 20 eyes of 10 patients undergoing LASIK using mechanical microkeratome Tear Break Up Time and Schirmer 2 tests are used to evaluate severity of dry eye before surgery and 1 , 3 and 6 months postoperative Follow up period : 6 months
Interventions
PROCEDUREtransepithelial PRK
PROCEDURELASIK
Sponsors
AL-Nour Eye Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* Myopia -1 to -6 diopters * Astigmatism -0.5 to - 4 diopters
Exclusion criteria
* Pregnancy and lactation * Keratoconus * Previous refractive surgery * Previous herpetic keratitis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| qualitative assessment of dry eye syndrome | 6 months | Tear Break Up time is used as a qualitative measure of dry eye after surgery |
| quantitative of dry eye after surgery | 6 months | Schirmer test is used as a quantitative measure of dry eye after surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| haze | 6 months | haze is a known possible complication of surface ablation Its severity can be graded according to a slit lamp scoring system |
Other
| Measure | Time frame | Description |
|---|---|---|
| healing time of epithelial defect epithelial defect | 2-5 days | the period of time in days needed for complete healing of the epithelial defect created during transepithelial PRK |
Countries
Egypt
Outcome results
None listed