Skip to content

The Role of Intravitreal Glucose in Macular Thinning Following Surgery for Retinal Detachment or Epimacular Membrane

Impact of Intravitreal Glucose Rate in Macular Thinning Following Retinal Detachment or Epimacular Membrane Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02210481
Acronym
GLU-MAC
Enrollment
60
Registered
2014-08-06
Start date
2014-02-28
Completion date
2014-12-31
Last updated
2017-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Thinning, Vitrectomy

Keywords

vitrectomy,, macular thinning,, retinal detachment,, epimacular membrane,, intravitreal glucose,, OCT

Brief summary

Comparison between intravitreous glucose rate and macular thinning measured by Ocular Coherence Tomography (OCT) at 3 months post vitrectomy for retinal detachment or epimacular membrane. Hypothesis : Association between post-operative macular thickness and intravitreous glucose rate

Detailed description

Comparison between intravitreous glucose rate and macular thinning measured by OCT at 3 months post vitrectomy for retinal detachment or epimacular membrane. The cohort is divided in 2 groups, one with the thinnest macular measurement under 190µm, and the others above 190µm. We are looking for a correlation between increasing glucose rates and decreased macular thickness.

Interventions

None listed

Sponsors

CHU de Reims
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* patient who underwent vitrectomy for retinal detachment or epimacular membrane

Exclusion criteria

* patient suffering of diabetes, * recurrence of retinal detachment, * age-related macular degeneration, * post surgical macular oedema

Design outcomes

Primary

MeasureTime frame
macular thickness measured by OCT3 months post-operatively

Secondary

MeasureTime frame
visual acuity3 months post-operatively

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026