Chronic Obstructive Airway Disease
Conditions
Keywords
chronic obstructive pulmonary disease, endurance training, interval training, continuous training, walking training
Brief summary
This study will investigate the effects of interval walking training versus continuous walking training in patients with chronic obstructive pulmonary disease. Patients will be recruited during a 3-week inpatient pulmonary rehabilitation program and will be randomized to one of the two intervention groups. All walking training sessions will be performed on the same treadmill. Walking intensity in the continuous walking group will be 60 percent of the average speed of the 6-minute walking test. Patients in the interval training group will perform high intensity intervals at 120% of the 6-minute walking test speed for 60 seconds alternating with 60 seconds of rest. The total exercise duration will be progressively increased from 10 to 32 minutes.
Interventions
Sponsors
Study design
Eligibility
Inclusion criteria
* COPD stage III or IV according to the Global Initiative for chronic obstructive lung disease \[GOLD\] * stationary patient in the Schön Klinik Berchtesgadener Land
Exclusion criteria
* acute, severe exacerbation of COPD * failure to comply with study process
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| perceived exertion for dyspnea during walking training | day 1 to 21 | measured via modified Borg scale (0 to 10) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| perceived exertion for leg fatigue (Borg-scale) | during three weeks of rehabilitation | — |
| Oxygen saturation during walking training | day 1 to 21 | measured via pulse oximeter |
| fat free mass in kilogram | day 1 to 21 | measured via Bioimpedance Analysis |
| forced expiratory volume in 1 second (FEV1) in liter | day 1 to 21 | measured by spirometry |
| heart rate during walking training | day 1 to 21 | — |
| 6-minute walking test | day 1 to 21 | the best 6-minute walking test out of two tests on admission and at discharge will be taken |
| 36 item short-form health Survey (SF-36) | day 1 to 21 | questionnaire for disease unspecific quality of life |
| chronic respiratory questionnaire (CRQ) | day 1 to 21 | disease specific quality of life questionnaire |
| hospital anxiety and depression scale (HADS) | day 1 to 21 | questionnaire on symptoms of anxiety and depression |
| Sit-to-stand-test | day 1 to 21 | 5 repetitions of standing up and sitting down from a chair with crossed arms as quick as possible |
Countries
Germany