Acute Lung Injury, Dietary Modification, Mechanical Ventilation Complication
Conditions
Brief summary
Patients with mechanical ventilation have shown improved weaning rates when enteral tube feeding high in EPA, GLA and antioxidants were fed to patients in the critical care setting. LTAC Patients on chronic mechanical ventilation will have decreased days an mechanical ventilation, decreased mortality rates and decreased organ failure when fed an enteral product high in EPA, GLA and antioxidants compared to an isotonic high fiber enteral nutrition product.
Interventions
OTHEROxepa
Therapeutic nutrition with EPA, GLA\< and antioxidants
OTHERJevity 1.5
Complete balanced nutrition with a unique fiber blend
Sponsors
Abbott Nutrition
Grace Hospital, Cleveland, Ohio
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\>18 years old with Respiratory failure on mechanical ventilation with failure to wean Diagnosis of ARDS (Acute respiratory Distress Syndrome) Bilateral infiltrates -
Exclusion criteria
History Of pulmonary fibrosis, Terminal illness/ malignancies, \<28 day life expectancy, Hemodialysis, Active bleeding or bleeding disorder: DIC ( Disseminated intravascular Coagulation), Sickle Cell Anemia, Hemophilia Hemorrhagic or ischemic stroke, Liver failure, Head trauma with Glasgow coma scale score of \<5, Immunosuppression: WBC(White Blood Cell Count) \<5000, HIV positive, use of immunosuppressant drugs, Pregnancy, and Heart Failure with EF(Ejection Fraction) \<35% \-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Length of days on mechanical ventilation | 14 days from start of enteral feeding |
Countries
United States
Outcome results
None listed