Cardiac Surgery
Conditions
Keywords
cardiac surgery, diaphragm dysfunction, mechanical ventilation weaning, respiratory paralysis, muscle weakness, cardiac bypass, valvular surgery, respiratory insufficiency
Brief summary
Diaphragm dysfunction is common after cardiac surgery and may delay weaning from mechanical ventilation and cause respiratory distress. The investigators' main objective is to determine the incidence of diaphragm dysfunction ( using the non-invasive ultrasonic method by calculating the inspiratory diaphragmatic thickening fraction) in a selected population of cardiac surgery patients during weaning from mechanical ventilation. The second endpoints are to determine the associated risk factors to post-operative diaphragm weakness and the consequence on the patient outcome.
Interventions
OTHERNon invasive ultrasound measurement of the diaphragm thickness during breathing
Sponsors
University Hospital, Grenoble
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 18 years old and older * planned surgery * ready for weaning from mechanical ventilation
Exclusion criteria
* protected patient * patient refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diaphragm inspiratory thickening fraction | At the begining of the spontaneous breathing trial (around 4hours after surgery) |
Secondary
| Measure | Time frame |
|---|---|
| Diaphragm dysfunction before surgery | the day before surgery |
| Severity score (Euroscore) | the day before surgery |
| extracorporeal circulation duration | peroperative |
| left ventricular ejection fraction | the day before surgery |
Countries
France
Outcome results
None listed