Distal Radius Fractures, Scaphoid Fractures, Wrist Injury Arthrodesis
Conditions
Brief summary
The brachial plexus block is an anesthetic technique often used for surgical procedures of the upper limb. To get the brachial plexus block, several routes can be used, including the axillary and infraclavicular approach. Few studies have compared these techniques, considering the time to perform the block, the onset time and success rate, with conflicting results. Furthermore, there is little information in the literature comparing the length of postoperative analgesia provided by these techniques. Therefore, the investigators designed this study in order to elucidate the differences between these two techniques to assist the anesthesiologist to choose the best of them in clinical practice.
Interventions
DEVICEUltrasound: Infraclavicular block
Ultrasound guided infraclvicular block
DRUGRopivacaine
20 ml of ropivacaine 0,5% in both groups ( axillary block and infraclavicular block)
DEVICEUltrasound: Axillary block
Ultrasound guided axillary block
Sponsors
Federal University of São Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* age older than 18 years and less than 70 years * consent informed signed by the patient * candidates for surgical intervention of scaphoid fractures, distal radius fractures and wrist arthrodesis * American Society of Anesthesiology physical status I, II and III * body mass index (BMI) \<35 kg / m².
Exclusion criteria
* cognitive impairment or active psychiatric condition * infection at the puncture site * bleeding disorders * history of allergy to ropivacaine
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| postoperative analgesia | first postoperative day | All patients will be contacted on the first postoperative day to tell the time of onset of pain postoperatively. The duration of postoperative analgesia is defined as the interval between the end of local anesthetic injection and the onset of postoperative pain reported by the patient. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| local anesthetic pharmacokinetics | During the procedure | Venous blood samples will be taken from some patients through a cannula. The samples will be used for the determination of serum levels achieved after ropivacaine blockade. Samples will be taken every 15 minutes during the first hour, every 30 minutes during the second hour and 4 hours after the blockade. These samples will be analyzed using the technique of high performance liquid chromatography coupled with mass spectrometry. |
Countries
Brazil
Outcome results
None listed