Acne, Scar
Conditions
Keywords
acne, acne scar, microneedling radiofrequency, bipolar radiofrequency
Brief summary
Compare the efficacy and safety profile of microneedling radiofrequency and that of bipolar radiofrequency treatment for acne scar.
Detailed description
Efficacy and safety of microneedling radiofrequency for acne scar Efficacy and safety bipolar radiofrequency treatment for acne scar compare the efficacy and safety profile of microneedling radiofrequency and that of bipolar radiofrequency treatment for acne scar
Interventions
DEVICEmicroneedling radiofrequency device
Microneedling radiofrequency device is composed of 49 insulated microneedle which emit radiofrequency from the needle tip. This radiofreqeuncy generates dermal heat which evokes biological effect.
DEVICEbipolar radiofrequency
bipolar radiofrequency instrument gives out bipolar radiofrequency from the hand piece tip. This bipolar radiofrequency generates dermal heat which has a lot of bilogical effect.
Sponsors
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
19 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* moderate acne scar * mild to moderate acne lesions
Exclusion criteria
* taking acne medication oral drugs within 2 months topical drugs within 2 weeks * taken anu procedures for acne scar within 6 months * taking steroid,nonsteroidal antiinflammtory drugs, isotretinoin * underlying diabetes mellitus, keloid, or any malignancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Global assessment of acne scar | 12 weeks | 5-point grading of acne scar quartile assessment of acne scar improvement through comparing the photos taken before treatment and after treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| ECCA | 12 weeks | quantitative assessment of acne scar ECCA assessment is established by previous article. this method quantifies severity of acne scar by counting the number of acne scar categorized by their shape. Then, the number of scars are multiplied by weighing factors determined by scar types. ECCA is the total sum of these points. please refer the Dreno et al, Dermatology, 2007;214:46-51 |
| Adverse effect | 12 weeks | adverse effects were measured by Epithelization Scale. ES is the total sum of evaluation of three components after wounding. please refer this article Min et al, Wound Repair and Regen, 2014;22(2):212-9 |
Countries
South Korea
Outcome results
None listed