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Postural Changes in Lung Volumes in Obesity

Effect of Weight Loss on Postural Changes in Pulmonary Function : a Longitudinal Study in Morbidly Obese to Obese Subjects Following Gastroplasty

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02207192
Enrollment
12
Registered
2014-08-04
Start date
2005-08-31
Completion date
2008-10-31
Last updated
2014-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

obesity, lung volumes, postural changes

Brief summary

Postural changes are known to affect normal lung volumes. A reduction in sitting to supine functional residual capacity (FRC) is well-described in non-obese subjects adopting a supine position. However, postural changes in lung volumes in the obese require further exploration. We aimed to longitudinally address the effects of weight loss on postural changes in lung volumes and pulmonary function, in obesity. We tested the hypothesis that supine reduction in FRC would be absent in morbid obesity and recovered upon weight loss.

Interventions

OTHERPostural change in lung volumes: sitting to Supine

Pulmonary function and arterial blood gases were assessed both prior to and after weight loss as part of pre-operative and 12-month follow-up evaluations. Pulmonary function tests were performed both in the sitting and then in the supine position.

Sponsors

Association pour la Formation du Personnel à la Medecine d'Urgence
Lead SponsorOTHER

Study design

Observational model
CASE_CROSSOVER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
No minimum to 60 Years
Healthy volunteers
No

Inclusion criteria

* subjects scheduled for bariatric surgery (BMI over or equal to 40 kg/m2)

Exclusion criteria

* Subjects with respiratory and cardiac history (asthma, COPD, heart failure) were excluded.

Design outcomes

Primary

MeasureTime frame
functional residual capacitybaseline and one year after bariatric surgery

Secondary

MeasureTime frame
lung volumes and flowsat baseline and after bariatric surgery

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 5, 2026