Obesity
Conditions
Keywords
obesity, lung volumes, postural changes
Brief summary
Postural changes are known to affect normal lung volumes. A reduction in sitting to supine functional residual capacity (FRC) is well-described in non-obese subjects adopting a supine position. However, postural changes in lung volumes in the obese require further exploration. We aimed to longitudinally address the effects of weight loss on postural changes in lung volumes and pulmonary function, in obesity. We tested the hypothesis that supine reduction in FRC would be absent in morbid obesity and recovered upon weight loss.
Interventions
Pulmonary function and arterial blood gases were assessed both prior to and after weight loss as part of pre-operative and 12-month follow-up evaluations. Pulmonary function tests were performed both in the sitting and then in the supine position.
Sponsors
Study design
Eligibility
Inclusion criteria
* subjects scheduled for bariatric surgery (BMI over or equal to 40 kg/m2)
Exclusion criteria
* Subjects with respiratory and cardiac history (asthma, COPD, heart failure) were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| functional residual capacity | baseline and one year after bariatric surgery |
Secondary
| Measure | Time frame |
|---|---|
| lung volumes and flows | at baseline and after bariatric surgery |
Countries
France