Combined Cataract Surgery and Planned Descemetorhexis

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02206594

Enrollment

Registered

2014-08-01

Start date

2014-01-31

Completion date

Unknown

Last updated

2015-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract, Fuchs' Corneal Dystrophy

Brief summary

A pilot study designed to assess the feasibility of planned descemetorhexis for the treatment of Fuchs' corneal dystrophy.

Interventions

PROCEDUREDescemetorhexis

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

General Inclusion Criteria: * Patient \>18 years old * Willing and able to provide informed consent Ocular Inclusion Criteria (all ocular inclusion criteria apply only to the study eye): * Fuchs' corneal dystrophy diagnosed * Cataract present * Best corrected visual acuity ≤ 20/40 * Candidate for current endothelial transplant procedure (DSAEK, DMEK) General

Exclusion criteria

* \<18 years old * Medically unstable patient * Monocular patient * Unwilling or unable to provide informed consent Ocular

Design outcomes

Primary

Measure	Time frame
Corneal clarity as assessed by slit lamp photography	Assessed up to 1 year following descemetorhexis

Secondary

Measure	Time frame
Resolution of edema as assessed by slit lamp photography	Assessed up to 1 year following descemetorhexis

Other

Measure	Time frame
Reconstitution of the endothelial cell layer as assessed by specular microscopy	Assessed up to 1 year following descemetorhexis

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026