Local Anesthesia
Conditions
Keywords
Central Venous Catheter, Remifentanil, local anesthesia, pain
Brief summary
At present, there is no reference protocol for Central Venous Catheter (CVC) insertion assuring analgesia, anxiolysis and safety. Medical teams use various levels of analgesia and anesthesia to realize this gesture, from single local anesthesia to general anesthesia. Remifentanil has been shown to decrease pain scores for insertion and removal of long-term central venous access. Remifentanil is also often employed for pediatric or labor analgesia for short acts as procedural sedation.
Interventions
DRUGRemifentanil
Pain's evaluation for Remifentanil Group
DRUGPlacebo
CVC pain's evaluation after local anesthesia + placebo infusion
Sponsors
University Hospital, Toulouse
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* more than 18 years old * eligible for CVC insertion
Exclusion criteria
* pregnancy * patients who can't give their consent * contra-indications to remifentanil infusion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximal pain score on numeric rating scale (NRS) will be assessed after the insertion | up to 60 minutes |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of patient's anxiety by the Face Anxiety Scale | up to 60 minutes |
| Patient and physician's satisfaction by a 10-points numeric rating scale | up to 60 minutes |
| Number of adverse events | up to 60 minutes |
| Number of realized punctions | up to 60 minutes |
Countries
France
Outcome results
None listed