Patients Affected by the HIV
Conditions
Keywords
HIV,, infection,, cohort
Brief summary
The purpose of this study is to improve our knowledge concerning HIV infection, treated or not, in the current conditions of care to optimize it.
Detailed description
Since the arrival of highly active tritherapies, HIV infection became mainly an ambulatory chronic pathology centred on a long term care taking into account the complication of long-term treatment as well as the arisen of new problem bound to a prolonged survival and ageing. So the care is more and more in a prevention and screening approach with in particular the care of metabolic and cardiovascular complication due to antiretroviral treatment. As a reorganization of the coverage of the HIV infected people take place on the Hotel Dieu Hospital it thus seems important to double this care optimization with a clinical research side. This will be done in constituting an HIV patient cohort including a blood sample collection to contribute to the vigilance of the complication to due the infection. Our ultimate objective is to optimize the selection of the treatment. It is important to do it to be able to have, on many years duration, precise clinical information and biological sample allowing to realize later some assay and analyse the influence of some genetic markers.
Interventions
BIOLOGICALOVIHD
7 ml of blood will be taken during a follow-up consultation and kept in a biological collection. Clinical data will be collected in a database.
Sponsors
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Aged ≥18 years old, * Patients with an HIV infection * patients having given their written informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HIV infection | 10 years | The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Comorbidity and complication in HIV infected patients | 10 years | The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient) |
| efficiency of the current antiretroviral therapeutic diets | 10 years | The HIV cohort will be constituted in collecting cardiovascular, neurological clinical data and medical past history (in case of women patient) |
| Blood sample collection | 10 years | To put in relation the clinical-biological relevant biological or genetic data of the follow-up a blood sample will be constituted. 7 ml will be taken to each patient and kept in a collection |
Countries
France
Contacts
STUDY_DIRECTORJean-Marc Tréluyer, MD, PhD
Assistance Publique - Hôpitaux de Paris
Outcome results
None listed