Cold Snare Polypectomy Vs. Cold Forceps Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps

Prospective Comparison of Cold Snare Polypectomy and Cold Forceps Polypectomy Using Narrow-band Imaging Endoscopy for Diminutive Colorectal Polyps

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02201147

Enrollment

146

Registered

2014-07-25

Start date

2014-07-31

Completion date

2014-11-30

Last updated

2015-05-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polyp of Large Intestine

Brief summary

The purpose of this study is to compare cold snare polypectomy and cold forceps polypectomy using narrow-band imaging endoscopy for removal of diminutive colorectal polyps.

Detailed description

Previous study found Cold snare polypectomy a preferable technique in comparison to cold biopsy for diminutive polyps when assessed for completeness of resection. However, it is expected that cold biopsy polypectomy with advanced endoscopy, such as chromoendoscopy or narrow-band imaging endoscopy, increase completeness of resection. One study showed 90% of the diminutive polyps were completely resected using cold biopsy polypectomy with chromoendoscopy. However, no study compared cold snare polypectomy and cold biopsy polypectomy using Narrow-band Imaging endoscopy for Removal of Diminutive Colorectal Polyps. The aim of this study is to compare cold snare polypectomy and Cold biopsy Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps

Interventions

PROCEDURECold biopsy polypectomy

removal of eligible polyps using cold biopsy technique until no polyp was visible by narrow-band imaging endoscopy

PROCEDURECold snare polypectomy

removal of eligible polyps using cold snare polypectomy technique

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

20 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* patients over the age of 20 years undergoing routine colonoscopy (screening, surveillance, or diagnostic)

Exclusion criteria

* patients taking antiplatelet or anticoagulant therapy during the past 1 week of the procedure * known coagulopathy * history of inflammatory bowel diseases * American Society of Anesthesiology class III or more * pregnancy.

Design outcomes

Primary

Measure	Time frame
complete histologic polyp eradication rate	2 weeks

Secondary

Measure	Time frame
rates of tissue retrieval per polyp	2 weeks

Other

Measure	Time frame
polypectomy procedure times	2 weeks

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 15, 2026