Adult Patients, Patient Covered by French Health Care System, Requiring Sedation in ICU
Conditions
Keywords
Sedation, Dexmedetomidine, ICU, Delirium
Brief summary
Research predictive factors of success or failure of a sedation with Dexmedetomidine in ICU
Detailed description
Prospective clinical study in ICU with sedated ventilated patients with dexmedetomidine, establishing incidence of success, failure of moderate sedation or failure of dexmedetomidine, to evaluate the effectiveness of this drug sedation in moderate sedation
Interventions
Sponsors
University Hospital, Clermont-Ferrand
Study design
Observational model
COHORT
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
-Adult patients ventilated requiring sedation in ICU with RASS objective more than -2
Exclusion criteria
* contraindication: intracranial lesion, hepatic failure * pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with failure of sedation with dexmedetomidine | at day 1 | Number of patients with failure of sedation with dexmedetomidine (necessity to stop this sedation due to adverse event, RASS\>+1, other) in ICU patients requiring such sedation during ICU stay. |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of adverse event of dexmedetomidine | at day 1 |
| Incidence of delirium and use of other sedative drugs | at day 1 |
Countries
France
Contacts
Primary ContactPatrick LACARIN
Outcome results
None listed