Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury

Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury- Assessment of Dialysis Adequacy and Infection Rates

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02200120

Enrollment

150

Registered

2014-07-25

Start date

2013-01-31

Completion date

2015-06-30

Last updated

2015-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Brief summary

Detailed description

The purpose of this study is to examine the placement, timing, associated complications, efficacy of temporary and tunneled catheters for renal replacement therapy in patient with acute kidney injury. In particular, we will be assessing renal replacement adequacy for patients on dialysis and continuous veno-venous hemofiltration by monitoring urea reduction ratios, venous and arterial pressures. We will also be monitoring infection rates. We will compare these outcomes in patients receiving tunneled catheters and patients receiving temporary catheters.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients admitted to the hospital with acute kidney injury requiring renal replacement therapy

Exclusion criteria

* End stage renal disease * Chronic kidney disease 5 progression to end stage renal disease * Outside hospital catheter placement

Design outcomes

Primary

Measure	Time frame	Description
Dialysis adequacy	up to 7d after starting renal replacement therapy	Adequacy will be measured using urea reduction ratio for patients on intermittent hemodialysis. For continuous renal replacement therapy, we will record the maximum blood flow rate achievable. These measurements/recordings will be made on average within 1-3 days of starting therapy.

Secondary

Measure	Time frame	Description
blood stream infection rates	within 30d of catheter placement	Patients will be followed throughout their hospitalization, which can range from a few days to several weeks. Bloodstream infections within 30d of catheter placement will be recorded.

Countries

United States

Outcome results