Magnesium as Adjuvant for Sciatic Block

Evaluation of Magnesium as Adjuvant to Ropivacaine for Sciatic Block at Popliteal Level.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02198547

Acronym

Enrollment

Registered

2014-07-23

Start date

2014-03-31

Completion date

2022-09-01

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hallux Valgus

Keywords

Local anesthetic adjuvant,, Magnesium solfatus,, Sciatic block

Brief summary

The aim of the study is to evaluate if Magnesium added to ropivacaine can reduce onset time and can enhance offset time.

Detailed description

Patients are randomly divided into two groups: group M (Ropivacaina 7,5 mg/ml with Mg 4 mg/Kg)and groupC (without Mg). Standard monitoring is applied to each patient in perioperative period. An indipendent observer collect data: time to perform block, sensitivity onset,motor onset, pain during surgery and complication. In the post-operative period till 24 hours for each patient is evaluated off-set time, pain and analgesic consumption.

Interventions

DRUGMagnesium Sulfate

Mg used with ropivacaine for sciatic nerve blick

DRUGRopivacaine

Ropivacaine 7,5 mg/ml used for sciatic nerve block

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* given consent * allux valgus correction surgery

Exclusion criteria

* allergy to local anesthetic * infection in the site of puncture

Design outcomes

Primary

Measure	Time frame	Description
Evaluation of Mg as adjuvant to local anesthetic	Till 24 hours	We evaluate if Mg affects onset and offset time of ropivacaine 7,5 mg/ml in sciatic block at popliteal level

Secondary

Measure	Time frame	Description
Post-operative pain	3 hours	We evaluate post-operative pain at rest and in movement at 3-6-12-24 hours with NRS scale
Post-operative analgesic consumption	till 24 hours	We evaluate consumption of opioid and non-opioid analgesic used in the post-operative period.
post-operative pain	12 hours	Evaluation of pain with NRS scale

Other

Measure	Time frame	Description
Patients' approval	At 24 hours	We evaluate the grade of approval of patients with a questionnaire

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026