Fecal Incontinence, Quality of Life
Conditions
Keywords
anorectal manometry
Brief summary
Background: High prevalence of fecal incontinence after rectal resection in patients with rectal carcinoma. Hypothesis: Anorectal manometry done before ileostomy or sigmoidostomy closure can predict fecal incontinence. Methods: Anorectal manometry before, 1 month and 6 month after closure. Anorectal endosonography before and 1 month after closure. Prediction of postoperative incontinence by the surgeon (digital sphincter examination). Visual analog scales for continence, subjective success of operation, and global well being; Wexner and Vaizey incontinence score; Parks incontinence classification; Rockwood fecal incontinence quality of life score; each before, 1 and 6 month after closure.
Interventions
None listed
Sponsors
German Society for Neurogastroenterology and Motility
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* all patients planned for ileo- or sigmoidostomy closure after rectal resection for rectal carcinoma
Exclusion criteria
* preoperative incontinence for solid stool * dementia * pregnancy * latex allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| predictive value of preoperative anorectal manometry for postoperative fecal incontinence | 6 month postoperative | Anorectal manometry is done preoperatively. Fecal incontinence is determined at 6 month postoperatively. Analysis of correlation between preoperative manometry parameter and incidence of postoperative fecal incontinence. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| fecal incontinence in patients with/without neoadjuvant radiochemotherapy | six month postoperative | Comparison of the percentage of patients with postoperative fecal incontinence after rectal resection in patients with or without neoadjuvant radiochemotherapy |
| predictive value of the surgeon's preoperative evaluation | six month postoperative | Clinical evaluation of the patient preoperatively with estimation (written statement) about postoperative continence/incontinence. Fecal incontinence is determined at 6 month postoperatively. Analysis of correlation between the surgeons´ predictions and the incidence of postoperative fecal incontinence |
Other
| Measure | Time frame | Description |
|---|---|---|
| prediction of postoperative fecal incontinence by the score of Stadelmaier and Matzel (Score =18.230 - 0.94x anastomotic level - 0.18 x resting pressure + 3.72 x radiochemotherapy (done 1, not done 0) | six month postoperative | Analysis of correlation between the preoperatively predicted Wexner score and the observed Wexner score six month postoperative. |
Countries
Germany
Contacts
Primary ContactChristian Pehl, MD
Outcome results
None listed