Identification of Corticomedullary Differentiation Along Different Stage of Pregnancy

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02193516

Enrollment

330

Registered

2014-07-17

Start date

2014-07-31

Completion date

2015-06-30

Last updated

2014-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nephropathy

Brief summary

Corticomedullary differentiation (CMD) abnormality (absent/reversed) is a parameter that can indicate possible nephropathy. The evolution of CMD across gestation had not been well established. Devrendt et al demonstrated the presence of CMD in all fetuses older then 20 weeks. In our study we would like to determine the exact timing of it's sonographic visualisation. This is a prospective study recruiting women between 14-24 week gestation during routine ultrasound screening. A midsagittal image of each kidney will be taken by a single sonographer and examined for the presence of the CMD by two other sonographers blinded to gestational age.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* pregnant women 14-24 weeks * singleton pregnancy * Appropriate for gestational age fetuses * well dated pregnancy

Exclusion criteria

* family history of renal disease * small /large for gestational age fetuses * known structural anomalies * unknown dating

Design outcomes

Primary

Measure	Time frame
CMD presence	A single exam for each participent. The photos will be reviewed within up to 6 month from examination date

Countries

Israel

Contacts

Primary ContactEfrat Hadi, MD

09-7472871

Outcome results