Apoptosis May Have a Role in Etiopathogenesis of Obstetric Cholestasis.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02192177

Enrollment

Registered

2014-07-16

Start date

2013-09-30

Completion date

2014-08-31

Last updated

2014-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnancy

Keywords

Apoptosis, intrahepatic cholestasis, obstetric outcomes

Brief summary

Intrahepatic cholestasis of pregnancy is a disease specific to pregnancy period; especially late second and third trimester. We aimed to investigate the role of apoptosis in etiopathogenesis of obstetric cholestasis.

Detailed description

M30 (caspases cleaved Cytokeratin-18 (CK-18) fragment) is a specific apoptosis marker. We aimed to use it to evaluate the apoptotic process.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Late second or third trimester of pregnancy.

Exclusion criteria

* Foreknown systemic diseases, multiple pregnancy, smoking cigarettes.

Design outcomes

Primary

Measure	Time frame
M30 value as Unit per Liter.	Four months.

Secondary

Measure	Time frame
Percentage of delivery with cesarean section.	Four months.

Countries

Turkey (Türkiye)

Contacts

Primary ContactAli O Ersoy

draliersoy@yahoo.com+905056579157

Outcome results