Type 1 Diabetes, Type 2 Diabetes
Conditions
Brief summary
This proposal seeks to gather continuous blood glucose and physical activity data from individuals with and without diabetes.
Detailed description
This proposal seeks to gather continuous blood glucose and physical activity data from individuals with and without diabetes who are physically active and exercising for health benefits. The investigators hypothesize that insulin requirements will be inversely related to intensity of activity and an algorithm will be able to detect physical activity and automatically adjust insulin doses. Once such an algorithm has been determined for an individual, it can be applied to future similar situations, but ideally the algorithm will be dynamically refined based on closed-loop feedback information.
Interventions
OTHERexercise
Sprinting, walking on a treadmill, and stationary bicycle riding
Sponsors
Sansum Diabetes Research Institute
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Inclusion criteria for subjects with diabetes * Type 1 diabetes or insulin requiring type 2 diabetes for at least 1 year * Use insulin to control diabetes * Physically active (regularly work out, swim, run, walk, bike, etc.) * Free of major micro- and macrovascular complications of diabetes * 18-75 years of age * A1C \< 9.0% Inclusion criteria for subjects without diabetes * No evidence of diabetes and physically active
Exclusion criteria
* unwilling to perform repeated glucose checks or take insulin as instructed * abnormal thyroid function, kidney function, liver function * pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Document the glycemic response of individuals without diabetes and with type 1 or type 2 diabetes | 7 days |
Countries
United States
Outcome results
None listed