Celiac Disease, Eosinophilic Esophagitis
Conditions
Brief summary
Celiac disease (CD) and eosinophilic esophagitis (EE) are distinct diseases of the gastrointestinal tract with specific clinico-pathological characteristics. In recent years, in the literature, several children who underwent upper gastrointestinal endoscopy for suspected CD, which was confirmed histologically, were also found to have coexistent EE. There are reports of coexistent CD and EE. We would like to see the prevalence of EE in children with CD and the prevalence of CD in children with EE in our population, and to do so would like to review medical records. Our objectives are to determine if children with celiac disease have a high prevalence of eosinophilic esophagitis.and to determine if children with eosinophilic esophagitis have increased risk of developing celiac disease.
Interventions
None listed
Sponsors
St. John Health System, Michigan
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to 21 Years
Healthy volunteers
No
Inclusion criteria
* Seen in the Pediatric Gastroenterology clinic at St. John Hospital & Medical Center during study time frame * Age 2-21 years old * Diagnosed with CD or EE or both based on the endoscopic and histopathological findings .
Exclusion criteria
* Gastroesophageal reflux diagnosed by PH probe. * History of chemical ingestion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Review of histopathology reports of esophageal biopsies to record the number of eosinophils per high power field. | Retrospective chart review study, no contact made with patients, so no patient time is required, expected average of 2 years |
Outcome results
None listed