Study on the Effect of Surgical Intestinal Manipulation

CD14/CD16 Activation in Brain-death Organ Donors and Effect of Surgical Intestinal Manipulation

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02189512

Acronym

IMMO

Enrollment

Registered

2014-07-14

Start date

2014-05-31

Completion date

2016-06-30

Last updated

2014-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intestinal Manipulation

Keywords

brain-death organ donors, intestinal manipulation, monocytes

Brief summary

The aim of this study is to study the impact of brain death and surgical small bowel manipulation on the release of different types of monocytes.

Interventions

OTHERblood sampling

cases - blood sampling controles - blood sampling

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* patients who are brain death * patients who undergo an elective abdominal aortic aneurysm repair

Exclusion criteria

* \< 18 years of age

Design outcomes

Primary

Measure	Time frame	Description
subtypes of monocytes	1 day	evaluate different subtypes of monocytes in brain-death donors by collecting portal and peripheral blood after lapaotomy and before dissection
evaluate effect of intestinal manipulation	1 day	evaluate the effect of intestinal manipulation on the different subtypes of monocytes and pro-/anti-inflammatory cytokines

Countries

Belgium

Contacts

Primary ContactLaurens Ceulemans, MD

Ceulemans.laurens@gmail.com+32 16 341545

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026