Infertility
Conditions
Brief summary
This clinical validation study is being carried out to validate the efficacy of a test measuring the clinical application of prostaglandins present in the endometrial fluid in patients, 24 hours before the embryonic transfer. This test is capable of predicting endometrial receptivity without the need of performing a biopsy.
Interventions
Extraction of endometrial fluid, analysis of prostaglandine and Day 3 embryo transfer
Extraction of endometrial fluid, analysis of prostaglandine and Day 5 embryo transfer
Sponsors
Igenomix
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Any IVF patient being treated for single or double embryo transfer * BMI: 20 - 30 * Normal ovarian response (7 - 8 ovocitos) in IVF treatment with AFC ≥ 8, (AFC = Antral Follicle Count) * Elective embryo transfer * Normal uterine cavity * Age: ≤ 38 years old for patients with own oocytes; ≤ 50 years old for patients with donated oocytes.
Exclusion criteria
* Patients with recurrent miscarriages ( ≥ 2 biochemical miscarriages; ≥ 2 clinical miscarriage) * Patients with severe male factor ( ≥ 2\*106 espermatozoides/ml).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| endometrial receptivity | 24 hours before embryo transfer | The endometrial samples will be extracted 24 hours before the embryo transfer in order to analyze the quantity of prostaglandins. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Implantation rate | 15 days | We will reffer a correlation between the prostaglandin results and the implantation rate. |
| Pregnancy rate | 15 days | We will reffer a correlation between the prostaglandin results and the implantation rate. |
Countries
Spain
Contacts
Primary ContactCarlos Gómez, MA
Outcome results
None listed