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Sensory Feedback for Touch and Proprioception With Prosthetic Limbs

Sensory Feedback Tactor Systems for Implementation of Physiologically Relevant Cutaneous Touch and Proprioception With Prosthetic Limbs

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02189031
Enrollment
21
Registered
2014-07-14
Start date
2013-02-01
Completion date
2023-11-17
Last updated
2026-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prosthetic

Keywords

Upper limb Amputee, Targeted Muscle Reinnervation, Prosthetic

Brief summary

Upper limb amputation is a devastating injury that leaves many thousands of typically young and active individuals in the US to rely on artificial arms and hands to help restore their lost function. The investigators research is focused on helping these individuals to feel where their prosthetic limbs are moving without having to look at them by developing devices and approaches to provide sensory feedback of limb movement through the nerves that once served the missing limb.

Detailed description

In the investigators research the investigators seek to understand the organization and (function/operation) of sensory neural systems in order to develop methods for restoring function to injured populations. One of the primary focus areas of the investigators research is working to integrate physiologically relevant sensory feedback with prosthetic limbs. To this end the investigators employ a variety of approaches that interweave disciplines such as electrophysiology, psychophysics, biomedical engineering and cognition. The investigators research team is composed of an interconnected and communicative network of clinicians, engineers, and scientists. This helps us to provide pathways from basic science discoveries that can be used to address clinical needs with transition directly to patient care.

Interventions

DEVICETactor array
DEVICEBypass Tactor

Sponsors

Louis Stokes VA Medical Center
Lead SponsorFED
National Institute of Neurological Disorders and Stroke (NINDS)
CollaboratorNIH
National Institutes of Health (NIH)
CollaboratorNIH
The Cleveland Clinic
CollaboratorOTHER
HDT Global
CollaboratorUNKNOWN
University of Alberta
CollaboratorOTHER
Shirley Ryan AbilityLab
CollaboratorOTHER
Defense Advanced Research Projects Agency
CollaboratorFED

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Amputee criteria: * Must be over 18 years of age * Must be upper extremity amputee who has undergone targeted sensory reinnervation. Able Bodied participants: * Must be over 18 years of age

Design outcomes

Primary

MeasureTime frameDescription
Embodiment of the Prosthetic limbTen monthsVisual loading for fine motor tasks,questionnaires, and residual limb temperature will be assessed after 10 months of in home every day use of a custom robust tactor array for sensory feedback.

Secondary

MeasureTime frameDescription
Investigate the perceptions of limb movement6 monthsTest how closely both targeted reinnervation amputees and able bodied study participants are able to interpret limb movement using the kinesthetic perceptual illusion and physiologically relevant kinesthetic feedback.

Countries

Canada, United States

Contacts

PRINCIPAL_INVESTIGATORPaul Marasco, PhD

Louis Stokes VA Medical Center, Cleveland Clinic Lerner Research Institute

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 2, 2026