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Irritable Bowel Syndrome and Low FODMAP Diet

Does Irritable Bowel Syndrome Improved by Low FODMAP Diet ?

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02188680
Acronym
FructIBS
Enrollment
112
Registered
2014-07-11
Start date
2014-01-01
Completion date
2018-01-01
Last updated
2026-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable Bowel Syndrome

Keywords

fructose test

Brief summary

The patients having a syndrome SII would be more intolerant in the fructose than the healthy subjects and would benefit from a fructose diet but also from the fructans which contain some fructose. The intolerance in the fructose is diagnosed thanks to a respiratory test after absorption of fructose. However, the eviction of the fructose is sometimes recommended to the patients without having realized beforehand the test of intolerance.

Detailed description

The main objective is to evaluate the efficacy of the FODMAPS diet on IBS symptoms and to correlate the results with the respiratory test

Interventions

FODMPAS low diet in patients with IBS and positive breath test for fructose FODMAPS low diet in patients with IBS and negative breath test for fructose

Sponsors

University Hospital, Rouen
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* older than 18, patients with IBS, patients with no organic disorders, patients informed and agreed to participate

Exclusion criteria

* patients with sclerodermia, diabetes, obesity, anorexia, colo-rectal surgery, patients with small intestinal bacterial overgrowth, pregnancy

Design outcomes

Primary

MeasureTime frameDescription
Fructose expiration rate (ppm)Day 15Estimate the value of the fructose test to predict the efficiency of a diet excluding the fructose and its by-products on the digestive symptoms of the patients having a Syndrome of the irritable bowel.

Countries

France

Contacts

PRINCIPAL_INVESTIGATORAnne-Marie LEROI, Professor

University Hospital, Rouen

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 3, 2026