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An Observational Study of OZURDEX® in Diabetic Macular Edema (DME)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02188173
Enrollment
200
Registered
2014-07-11
Start date
2014-07-31
Completion date
2016-05-31
Last updated
2016-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macular Edema

Brief summary

This is a study of OZURDEX® use in clinical practice in patients with diabetic macular edema (DME).

Interventions

Patients who receive dexamethasone 700 ㎍ (OZURDEX®) intravitreal implant treatment for Diabetic Macular Edema. All decisions regarding treatment are made at the sole discretion of the treating physician in accordance with their usual practices.

Sponsors

Allergan
Lead SponsorINDUSTRY

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Diagnosis of DME in at least one eye treated OZURDEX® per clinical practice

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frame
Maximum Change from Baseline in Best Corrected Visual Acuity (BCVA) in the Study EyeBaseline, 12 Months
Percentage of Patients with a BCVA Improvement of ≥15 Letters in the Study EyeBaseline, 12 Months
Average Change from Baseline in BCVA in the Study EyeBaseline, 12 Months

Secondary

MeasureTime frame
Mean Number of Ozurdex Injections in the Study Eye12 Months
Percentage of Patients with an Increase from Baseline of ≥2 Lines in BCVA in the Study EyeBaseline, 12 Months
Change from Baseline in Central Retinal Subfield Thickness (CRT) in the Study EyeBaseline, 12 Months
Mean Time Between Ozurdex Injections in the Study Eye12 Months
Percentage of Patients with an Increase from Baseline of ≥3 Lines in BCVA in the Study EyeBaseline, 12 Months
Percentage of Patients with BCVA of 20/40 or Better in the Study EyeBaseline, 12 Months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026