Safety and Effectiveness Study of a Non-Crosslinked HA Alkylamide HYADD(TM) 4 Hydrogel for Osteoarthritis of the Knee

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02187549

Enrollment

332

Registered

2014-07-11

Start date

2014-06-30

Completion date

2016-03-31

Last updated

2015-10-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis

Keywords

Hyaluronic Acid, Osteoarthritis, Knee, Hyaluronan, Viscoelastic, Hydrogel

Brief summary

The purpose of this study is to determine whether intra-articular hyaluronic acid provides symptomatic relief of osteoarthritis of the knee.

Interventions

DEVICEHYMOVIS

Intra-articular injection

DEVICEPlacebo

Intra-Articular Injection

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

40 Years to No maximum

Healthy volunteers

Inclusion criteria

* Symptomatic osteoarthritis of the knee.

Exclusion criteria

* No disorders which could interfere with study required assessments.

Design outcomes

Primary

Measure	Time frame
Western Ontario and McMaster Universities Osteoarthritis (WOMAC) Pain Sub-score	26 weeks

Secondary

Measure	Time frame
Patient Global Assessment	26 weeks

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026