T2 Weighted Imaging of the Liver With Fast Spin Echo MRI

Enhancement of T2 Weighted Imaging of the Liver With Fast Spin Echo Magnetic Resonance Imaging (MRI).

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02186054

Enrollment

Registered

2014-07-10

Start date

2014-06-30

Completion date

2016-06-30

Last updated

2015-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Disease

Keywords

Abdominal-Pelvic MRI (magnetic resonance image), T2W (T2 weighted), FSE Flex (recently developed MRI pulse sequence), Enhanced single shot FSE (fast spin echo).

Brief summary

The purpose of this study is to test two new MRI (magnetic resonance imaging) sequences to see how they compare to previously used imaging sequences as they may improve the quality of abdominal MRI.

Detailed description

* Approximately 50 patients undergoing routine liver MRI in our practice imaged with one of our 4 clinical scanners will undergo our standard liver MRI protocol with the addition of 2 breath-hold sequences (FSE Flex and eSSFSE) only increasing the scan time by approximately 3 minutes. * Data will be retrieved from examinations that have been performed from the patient's electronic imaging file stored in our picture archiving and communication system (PACS). * Images will be completely anonymized. No patient identifiers will be available on the images during the analysis. * Analyses will include the visual assessment of image quality, presence and severity of imaging artifact and other non-invasive imaging outcomes performed by radiologists blinded to patient information and the type of sequence performed. Data will be presented in a Likert type scale (1=poor, 2=suboptimal, 3=average, 4=above average and 5=excellent) and imaging parameters will be compared using the Wilcoxon sign rank test.

Interventions

DEVICEMRI examinations

Consented patients will be required to stay in the MRI scanner to complete the 2 additional sequences once their standard exam is completed.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients undergoing routine liver MRI imaged with one of our 4 clinical scanners (MR 750W, General Electric, Milwaukee WI)

Exclusion criteria

* Patients not undergoing routine liver MRI

Design outcomes

Primary

Measure	Time frame	Description
The number of abdominal MRI scans deemed improved quality	Regular scan time with one of 4 clinical scanners plus 3 additional minutes	Data is presented in a Likert type scale (1=poor, 2=suboptimal, 3=average, 4=above average and 5=excellent) and imaging parameters are compared using the Wilcoxon sign rank test.

Secondary

Measure	Time frame	Description
The number of MRI scans that display severity of imaging artifact	Regular scan time with one of 4 clinical scanners plus 3 additional minutes	Data is presented in a Likert type scale (1=poor, 2=suboptimal, 3=average, 4=above average and 5=excellent) and imaging parameters are compared using the Wilcoxon sign rank test.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026