Verticality Perception in Stroke
Conditions
Brief summary
The long-term goal of this research is to advance our knowledge of how information from the labyrinth is brought to perception and how adaptation to vestibular imbalance influences spatial orientation. In healthy human subjects verticality perception is accurate while upright.The strategy of this research is to quantify changes in verticality perception after unilateral lesions along the central graviceptive pathways and to assess the frequency and pattern of abnormal verticality perception in patients with acute stroke (ischemic or hemorrhagic). Our underlying hypothesis is that screening for erroneous verticality perception by use of a mobile device assessing the subjective visual vertical (SVV) during the acute phase (i.e., within 24-48 hours after symptom onset) reliably identifies those patients with defects. Early detection of deficits in verticality perception may help to initiate balance physiotherapy early.
Interventions
OTHERpresentation of visual vertical
Sponsors
University of Zurich
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
1. ages 18-90 years 2. informed consent 3. for group 1: acute (i.e. symptom onset \<3 days ago) lateralized ischemia or hemorrhage as confirmed by clinical examination and / or brain imaging (CT or MRI). 4. absence of
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy of verticality perception | during the measurement period (10 minutes) |
Secondary
| Measure | Time frame |
|---|---|
| Test-re-test reliability of verticality perception | from session 1 (day 0) to session 2 (day 1) |
Countries
Switzerland
Outcome results
None listed