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Nutrition and Neurological Development of Very Preterm Infants

Early Nutrition and Neurological Development of Very Preterm Infants

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02184650
Acronym
EPINUTRI_3
Enrollment
206
Registered
2014-07-09
Start date
2014-07-31
Completion date
2017-12-31
Last updated
2025-11-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Delayed Mental Development, Infant Nutrition Disorders, Premature Infant

Keywords

Premature infants, Nutritional status, Polyunsaturated fatty acids status

Brief summary

The main goal of this study is to determine, in preterm infants born with a GA \< 32 weeks, the association between: * the quantity of mother's milk and duration and breastfeeding * the intake of polyunsaturated fatty acids and iron during hospitalizations

Detailed description

The main hypothesis of this study is that the intake of lipid during hospitalization in neonatology department is associated with neurological development of preterm infants born with a GA \< 32 weeks. The other hypotheses are that iron intake and the duration of breastfeeding are also associated with the development of preterm infants. In the previous study EPINUTRI (NCT01486173), the development of infants was evaluated until the age of 1 year. EPINUTRI\_3 is the follow-up of EPINUTRI until the age of 3 years. The aim of EPINUTRI\_3 study is to determine the association between lipid intake during hospitalization in neonatology department of preterm infants born with a GA \< 32 weeks. The secondary objective is : \- to evaluate the association between these factors and communication, developmental and social-emotional delays with the test Ages and Stages questionnaire (ASQ) at 3 years of age.

Interventions

OTHERPremature infants with a GA < 32 weeks

At 3 years of age: ASQ (filled in by parents)

Sponsors

URC-CIC Paris Descartes Necker Cochin
CollaboratorOTHER
Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
3 Years to 3 Years
Healthy volunteers
No

Inclusion criteria

* Premature infants previously included in EPINUTRI study * Non opposition of the parents for the collection of clinical and nutritional data

Exclusion criteria

* Refusal of the parents to collect clinical and nutritional data

Design outcomes

Primary

MeasureTime frameDescription
Neurological developmentAt 3 years of ageAge and Stages Questionnaire

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026