Gestational Diabetes Mellitus, Polycystic Ovary Syndrome
Conditions
Keywords
PCOS, GDM, OGTT, Glucose metabolism
Brief summary
Women with polycystic ovary syndrome (PCOS) are often insulin resistant. During pregnancy, insulin sensitivity decreases. The investigators examine glucose metabolism during oral glucose tolerance test and the incidense of gestational diabetes mellitus in a prospective cohort of pregnant women with PCOS and controls.
Interventions
OTHEROGTT by randomization
OTHEROGTT by indication
Sponsors
Region of Southern Denmark
Municipality of Odense
University of Southern Denmark
Odense University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Pregnancy achieved during 2010-2012 * Residents of the municipality of Odense
Exclusion criteria
* Moving from Odense during pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Gestational diabetes mellitus | 2 years | Gestational diabetes mellitus diagnosed by oral glucose tolerance test in gestational week 28 in women with and without risk factors for gestational diabetes mellitus. |
| Gestational Diabetes Mellitus | Gestational week 28 | Gestational diabetes mellitus is diagnosed by 2 hour 75 gram oral glucose tolerance test in gestational week 28 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anthropometric measures in offspring | At birth | The association between blood glucose values and anthropometric measures (birth length, weight and abdominal circumference) at birth in the offspring is investigated |
Countries
Denmark
Outcome results
None listed