FDG PET-Scan Analysis of Evolutivity of Non-surgical Aneurysm of Abdominal Aorta

ANALYSE EN MORPHO-TEP AU FDG DE L'EVOLUTIVITE DES ANEVRISMES ABDOMINAUX AORTIQUES NON CHIRURGICAUX UNE ETUDE MULTICENTRIQUE DE L'INTER-REGION NORD-EST

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02182908

Acronym

AAA

Enrollment

Registered

2014-07-08

Start date

2007-03-31

Completion date

2013-05-31

Last updated

2021-08-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medically-treated Aneurysm of Abdominal Aorta

Keywords

Aneurysm of abdominal aorta, 18F-fluorodesoxyglucose (FDG-F18)

Brief summary

The primary aim of the study is to determine if the evolutivity of global and segmentary captation of FDG-F18, which can be measured in the wall of abdominal aorta aneurysm, is predictive of the 9 month evolution of diameter and volume of the aneurysm, measured globally and segmentary in angioscan.

Interventions

OTHERPET-Scan

PET-Scan

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

SCREENING

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* AAA with a minimum diameter of 40 mm, calculated with a standardized method * No indication for an immediate surgery or endoprothesis implantation * Age above 18 (except for patient under supervision) * Patient having read the information letter and signed the informed consent

Exclusion criteria

\- AAA should have no other specific cause than atherosclerosis

Design outcomes

Primary

Measure	Time frame	Description
Association between overall baseline 18-FDG uptake intensity of the aneurysm and its 9-month maximal diameter and/or volume in patients with diameter change greater than 4 mm/year	9 months	Composite primary outcome.

Secondary

Measure	Time frame
Association between initial 18-FDG uptake of individual aneurysmal segments and their 9-month diameter change.	9 months
Contribution of overall 18-FDG uptake to the predictive values of other baseline characteristics of the aneurysm (diameter, volume, thickness and wall stress, clinical and biological values)	9 months
Association between overall 18-FDG uptake and other baseline characteristics of the aneurysm (diameter, volume, thickness and wall stress, clinical and biological values).	9 months
Association between 9-month overall 18-FDG uptake change and variation of plasmatic biomarkers of inflammation, proteolysis and coagulation.	9 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026