Postdural Puncture Headache, Sphenopalatine Ganglion Block
Conditions
Brief summary
The investigators are attempting to determine a less invasive method of treatment for postdural puncture headaches that can occur after regional anesthesia. The investigators will be evaluating the relief of headache with those subjects receiving treatment with a sphenopalatine ganglion block with bupivacaine versus placebo, evaluating the incidence of epidural blood patch, pain score of headache at 1 hour, then 24, 48, and 72 hours lower with post study treatment versus placebo, and potential side effects of those patients receiving study therapy as well as epidural blood patch.
Interventions
DRUGbupivacaine
DRUGplacebo
Sponsors
Wake Forest University Health Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologists assigned class I-III * age \>/= 18 years * experiencing a postdural puncture headache within 7 days of neuraxial analgesia rated \>3/10 pain score
Exclusion criteria
* allergy to study medications \<18 years of age pain score on presentation \</=3/10 for headache
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| verbal pain score | 1 hour | a reduction in headache verbal pain score by 3 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| epidural blood patch | 7 days | evaluating the decrease in the necessity of an epidural blood patch to treat the postdural puncture headache |
| patient satisfaction | 1 hour | patient satisfaction with headache pain relief at 1 hour post treatment |
| pain score | 30 minutes | verbal pain score 30 minutes post study treatment |
Countries
United States
Outcome results
None listed