Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02179905

Enrollment

Registered

2014-07-02

Start date

2013-01-31

Completion date

2013-09-30

Last updated

2014-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Irritable Bowel Syndrome

Keywords

MRI, Heart rate variability, Fatty acid

Brief summary

This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.

Detailed description

Several studies showed that the gray matter and white matter of the brain related to the symptoms of irritable bowel syndrome patients. The investigators study is to analyse the relationship between thickness of cortex of irritable patients, the sympathetic tone and the serum fatty acid component of the irritable bowel syndrome patients. It is to clarify the mechanism of irritable bowel syndrome, whether the symptoms of irritable bowel syndrome are related to the thickness of cortex or inflammation status of the body.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* female * between 20 and 50 years old * meet Rome III criteria

Exclusion criteria

* colon and small intestinal disease * psychiatric disease patients * patients received major surgery in the past 5 years * diabetic patients * patients with metal implant

Design outcomes

Primary

Measure	Time frame
The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients.	Patients who suffered from IBS for more than 5 years.

Secondary

Measure	Time frame
The relationship between thickness of brain cortex and the symptoms of irritable bowel syndrome	Patients who suffered from IBS for more than 5 years.

Other

Measure	Time frame
The relationship between heart rate variability and symptoms of irritable bowel syndrome patients.	Patients who suffered from IBS for more than 5 years.
The relationship between component of fatty acid and symptoms of irritable bowel syndrome patients.	Patients who suffered from IBS for more than 5 years.

Countries

Taiwan

Outcome results