Performance of Non-Invasive Monitors During ANH

The Evaluation of Minimally Invasive Hemodynamic Monitors for the Assessment of Volume Responsiveness to Various Standard Replacement Fluids During Acute Normovolemic Hemodilution

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02179827

Enrollment

Registered

2014-07-02

Start date

2022-11-30

Completion date

2024-11-30

Last updated

2022-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Baseline, Hemodilution

Brief summary

The aim of this study is to assess the responsiveness of the standard minimally invasive hemodynamic monitors used in the operating room to known changes in the intravascular volume status that occur during blood removal and volume replacement with three different standard fluids used during ANH.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Those surgical procedures where ANH is included in the surgical plan and consent is obtained

Exclusion criteria

* Severe or symptomatic COPD, emphysema, renal, hepatic or coronary artery disease as defined by the American College of Cardiology (Cannon et al., 2001). * Esophageal pathology (diverticulum, hiatal hernia, esophageal cancer, esophageal surgery), which introduces risks associated with the placement of the esophageal Doppler. * Ascites. * BMI \>35 * Pregnancy

Design outcomes

Primary

Measure	Time frame	Description
Change in cardiac output	Baseline (Supine) Volume Replaced (S/P ANH)	Metrics: Cardiac output stroke volume Stroke volume: variation

Countries

United States

Outcome results