AAA, Abdominal Aortic Aneurysm
Conditions
Keywords
Abdominal aortic aneurysm, AAA, Screening
Brief summary
The aim of the cohort study SCAN (Screening Cardiovascular patients for Aortic aNeurysms) is to establish a screening programm for patients with a high risk for an AAA. Aortic aneurysms in these patients should be identified at an early stage and thereby AAA-associated mortality be decreased.
Detailed description
A recently published meta-analysis showed a higher prevalence of aortic aneurysm (AAA) in men requiring treatment of coronary heart disaese compared to standard population. In women, however, the prevalence was not increased. Thus, the SCAN project addresses male patients who underwent coronary artery intervention in order to screen them for the presence of an AAA using duplex sonography. The SCAN project involves the following elements: 1. Informing the patient with cardiovascular risk factors about the clinical picture of AAA 2. An ultrasound scan of the abdominal aorta in patients with an increased risk for AAA 3. Acquisition of patient data followed by a correlation analysis for the parameters presence of AAA and cardiovascular diseases The cohort study is part of the SCAN project which is also conducted in an similar way by Catharina Ziekenhuis Eindhoven ClinicalTrials.gov Identifier:NCT01643317.
Interventions
None listed
Sponsors
I. Medizinischen Klinik und Poliklinik, Technical University of Munich
Technical University of Munich
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Healthy volunteers
No
Inclusion criteria
* men with coronary artery intervention (PTCA/stenting) * at least 1 risk factor for AAA (hypertension, hyperlipidaemia, hyperuricemia, nicotine abuse,positive family history)
Exclusion criteria
* life expectancy less than 1 year * inability to follow the instructions of the investigator (dementia, lack of time, insufficient understanding of the language) * insufficient compliance
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of AAA | 1 year | Ultrasound screen for the presence of an AAA |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Prevalence of AAA in the cohort requiring treatment | 1 year | Measuring the AAA diameter |
| Correlation of risk factors for AAA with risk factors for coronary artery disease | 1 year | Therefore the cardiovascular risk factors ( diabetes, hypertension, hyperlipidaemia, hyperuricemia, nicotine abuse, positive family history, obesity) will be requested. |
| Distribution of risk factors | 1 year | Distribution of cardiovascular risk factors (diabetes, hypertension, hyperlipidaemia, hyperuricemia, nicotine abuse, positive family history, obesity) between patients with an without an AAA |
| Correlation of the number of treated vessels and AAA | 1 year | — |
Countries
Germany
Contacts
Primary ContactHans-Henning Eckstein, Univ.-Prof.Dr.med.
Backup ContactBenedikt Reutersberg, Dr. med.
Outcome results
None listed