Preliminary Study of the Scale To Assess Ataxia and Neurologic Dysfunction (STAND)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02179333

Acronym

STAND

Enrollment

Registered

2014-07-01

Start date

2012-10-31

Completion date

2016-06-30

Last updated

2021-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Friedreich's Ataxia, Spinocerebellar Ataxia - All Sub-types

Brief summary

The objectives of this study are: * To validate the inter-rater and intra-rater reliability of a new scale for the assessment of ataxia and neurologic dysfunction (STAND) * To assess common constructs and correlation between STAND subscale items.

Detailed description

There are few validated, comprehensive rating scales for the assessment of ataxia severity. The development of a Scale To assess Ataxia and Neurologic Dysfunction (STAND) would examine and measure as many facets of ataxia as possible. Scale items to be measured include parkinsonism, timed gait analysis, dystonia, neuropathy and peripheral nerve weakness, as well as other areas of clinical manifestation for ataxia. This brief but thorough scale should yield a thorough measurement of ataxia.

Interventions

OTHERAtaxia rating scale

Administer new rating scale for ataxia. This will be administered by two different raters on two separate occassions, 4 to 6 weeks apart.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Diagnosis of ataxia. * Male or female between 18 and 80 years of age. * Subject has voluntarily signed an IRB approved informed consent form to participate in the study after all relevant aspects of the study have been explained and discussed with the subject.

Exclusion criteria

* Any illness that in the investigator's opinion preclude participation in this study. * Subjects with a cardiac pacemaker * Legal incapacity or limited legal capacity.

Design outcomes

Primary

Measure	Time frame	Description
Inter- and intra-rater agreement	4 to 6 weeks	Assess agreement between raters (inter-rater agreement) and within raters (intra-rater agreement) through the evaluation of STAND total score, subtotals and individual variables using intraclass correlation coefficients (ICCs).

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026