Orthostatic Hypotension
Conditions
Keywords
Orthostatic hypotension in the elderly, Efficacity of Hydration, Difference between hydratation and venous contention
Brief summary
Primary objective: To compare the decrease in systolic blood pressure between hydration and venous contention when switching to a standing position. Hypothesis in that hydration is better than venous contention. Secondary objective: To evaluate the effect of hydration on lowering systolic blood pressure during the passage standing in elderly patients with orthostatic hypotension. Inclusion criteria: Patient aged over 75 years old with orthostatic hypotension proved to 1 and / or 3 min
Detailed description
Day 0: confirmation of the orthostatic hypotension, without prevented measures Two groups randomized : * Group 1: First day (day 1), Orthostatic Hypotension test after hydration by three large glasses of clear liquid (33cl). Second day (day 2), Orthostatic Hypotension test with venous contention in the morning. * Group 2: First day (day 1), Orthostatic Hypotension test after implementation of venous contention in the morning. Second day (day 2), Orthostatic Hypotension after hydration by three large glasses of clear liquid (33cl).
Interventions
OTHERHydration
Hydratation the first day in the arm 1 Hydration the second day in the arm 2
OTHERVenous contention
Venous contention the second day in the arm 1 Venous contention the first day in the arm 2
Sponsors
Central Hospital, Nancy, France
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
75 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patient aged 75 and older with orthostatic hypotension proved to 1 and / or 3 minutes. * Written consent of the subject * Hospitalization or stay expected minimum 3 days * Affiliation to a social security scheme
Exclusion criteria
* bedridden patient or without possibility of verticalization * Patient who can't stand up (pulmonary embolism with high risk) * Patient who refuse to participate in the study * Patient with legal protection * State or condition that may affect the stability of blood pressure during the study (hyperthermia, modification antihypertensive treatments less than 48 hours before inclusion...) * Pathology preventing hydration: Heart failure with less than 1 Liter water restriction, swallowing disorders preventing hydration orally, inability to nutrition and hydration orally * Intravenous or subcutaneous hydration (intravenous or subcutaneous treatments not included) * Patient who can't have venous contention: Blue phlebitis, septic thrombosis, arteritis with score less than 0.6, varicose ulcers during treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| difference in systolic blood pressure between sitting and standing at 1 and 3 minutes between hypotension test with hydration and hypotension test with venous contention | during 3 days: day 0, day 1, day 2 |
Secondary
| Measure | Time frame |
|---|---|
| difference in systolic blood pressure between sitting and standing at 1 and 3 minutes between hypotension test with hydration and hypotension test without prevention | during 3 days: at day 0, day 1, day 2 |
Countries
France
Contacts
Primary ContactAthanase Benetos, Pr
Backup ContactMarion Serot Gresser
Outcome results
None listed