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Effectiveness of Internet-based Depression Treatment (EVIDENT) in Severe Depression

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02178631
Enrollment
163
Registered
2014-07-01
Start date
2013-02-28
Completion date
2014-05-31
Last updated
2015-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe Depressive Symptoms

Brief summary

Online self-help is an innovative way of providing self-help. The investigators want to study the effect of an interactive online self-help-program (Deprexis) in the treatment of severe depressive symptoms. Participants will be randomised to either twelve weeks of online-self help or a waiting-list control. Symptoms of depression and other aspects will be assessed over a six months period. The investigators hypothesise that online self-help is superior to the control condition in alleviating depressive symptoms and preventing full blown depression.

Interventions

BEHAVIORALDeprexis

Online self-help

OTHERCAU

Care as usual

Sponsors

Björn Meyer, Gaia AG, Hamburg, Germany / Department of Psychology, City University, London, United Kingdom
CollaboratorUNKNOWN
University of Hamburg-Eppendorf
CollaboratorOTHER
University of Bern
CollaboratorOTHER
University of Luebeck
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Age between 18 and 65, ability to read German, willingness to participate in a telephone diagnostic interview, achieving a score of at least 15 on the PHQ-9 in an initial screening, and providing written informed consent

Exclusion criteria

* Lifetime diagnosis of schizophrenia or bipolar disorder (as determined by a telephone diagnostic interview) or current suicidality (as determined in a telephone interview)

Design outcomes

Primary

MeasureTime frame
Patient Health Questionnaire - 9 items (PHQ-9)Change from Baseline to post (3mths).

Secondary

MeasureTime frame
Quick Inventory of Depressive Symptoms - Self-Rreport (QIDS-SR16)Baseline, post (3 mths), follow-up (6 mths)
Generalized Anxiety Disorder - 7 (GAD-7)Baseline, post (3 mths), follow-up (6 mths)
Patient Health Questionnaire - 15 items (PHQ-15)Baseline, post (3 mths), follow-up (6 mths)
Short Form Health Survey - 12 (SF-12)Baseline, post (3 mths), follow-up (6 mths)

Countries

Germany, Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 15, 2026