Prolongation of Pain Free Time by the Use of Dexamethasone in Peripheral Nerve Blockade

The Effect of Dexamethasone Used Together With Low Volume Ropivacaine in a Single Shot Interscalene Block on the Pain Free Time Experienced by the Patient

Status

UNKNOWN

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02178449

Enrollment

109

Registered

2014-06-30

Start date

2014-03-31

Completion date

2015-05-31

Last updated

2014-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Interscalene Block, Shoulder Arthroscopy, Dexamethasone, Low Volume Regional Anesthesia

Brief summary

The main aim of the study is to investigate the proven effect of dexamethsone on the duration of the interscalene block. The investigators try to define optimal dose and volume for ropivacaine, when used together with dexamethsone. The current literature uses often very high volumes of ropivacain when used together with dexamethasone. The investigators try to research the effect of using dexamethsone together with low volume, high concentration ropivacaine for interscalene blockade. The investigators' hypothesis is that dexamethasone has an positive effect on the pain free after used together with ropivacaine at the scalene block.

Interventions

DRUGDexamethasone acetate

DRUGPlacebo

DRUGRopivacaine

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* atroscopy of the shoulder * repair of the RM

Exclusion criteria

* patient under 18 years * patient is fertile * chronic opiat use more than 30mg oxycodone per day * operations at the shoulder that involves the bone * usage of cortisone for more than 2 weeks * risk greater as asa III * damage to nerves * neuropathy at the target arm

Design outcomes

Primary

Measure	Time frame
Pain free time measured by the duration between block and the point at which the patient is asking for painkillers	Patients will be followed during their stay at the hospital, which will be normally around 24 to 48 hours.

Secondary

Measure	Time frame
Visual Rating Scale for Pain at Movement and Rest	Measured 10 hours after the intervention

Other

Measure	Time frame	Description
Patient satisfaction	1 day, when the patient leaves the hospital	Measured by a validated questionary

Countries

Austria

Contacts

Primary ContactChristoph Hörmann, MD

office@stpoelten.lknoe.at+ 43 2742 9004

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026