Clinical Investigation on Zirconia-ceramic Three-unit Bridges With CAD-on Veneering

A Randomized Clinical Trial of 3-unit Posterior Zirconia-ceramic Fixed Dental Prosthesis (FDPs) Veneered With Layered and Milled (CAD-on) Veneering Ceramics

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02175329

Enrollment

Registered

2014-06-26

Start date

2010-01-31

Completion date

2017-12-31

Last updated

2020-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Three-unit Posterior Bridges

Keywords

CAD/CAM, three-unit posterior bridges, zirconia framework

Brief summary

60 bridge frameworks are CAD/CAM manufactured from zirconia-ceramic; 30 bridges are veneered with CAD/CAM fabricated lithium disilicate ceramic, 30 bridges are manually layered. The goal is to compare clinical survival , biological or technical behaviour of the restorations.

Detailed description

Randomized prospective controlled clinical study with three-unit posterior bridges made of zirconia-ceramic to compare veneering with manually layering or CAD/CAM fabricated lithium disilicate ceramic veneers. The hypothesis is that there is no difference in clinical survival of the restorations and no difference in biological or technical behaviour.

Interventions

DEVICECAD/CAM Veneering

CAD/CAM fabricated zirconia bridge framework is veneered with CAD/CAM fabricated lithium disilicate ceramic veneer

DEVICEManually layered veneering

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* single missing posterior tooth with two adjacent posterior teeth * no acute conservative or paradontal treatment need except for the teeth to be treated in the study * sufficient oral hygiene

Exclusion criteria

* known allergies to components * bruxism * missing antagonist tooth * pregnancy or lactation * missing written consent * patients which are not expected to be compliant * severe systemic diseases * untreated carious lesions * untreated parodontitis

Design outcomes

Primary

Measure	Time frame	Description
Number of participants with clinical success	2 years	Clinical success is defined as more than 95% survival of the restoration after 2 years.

Secondary

Measure	Time frame	Description
Restoration quality	1 week, 1 year, 2 years, 3 years, 4 years, 5 years	Characterisation of the restorations according to United States Public Health Services (USPHS) criteria

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026