Bowel Preparation, Pediatric Colonoscopy
Conditions
Keywords
Pediatric Colonoscopy, Bowel Preparation, Safety, Tolerability
Brief summary
This was a blinded study conducted on the efficacy and safety of a one-day versus a three-day bowel preparation in a pediatric population. Limited data is available in this regard, and this study supports the use of a one-day bowel preparation, as this is both safe and effective.
Detailed description
Colonoscopy in children and young adults is performed by gastroenterologists for a variety of indications, including but not limited to evaluation of rectal bleeding, chronic diarrhea, family history of polyposis syndromes and surveillance for colon cancer in patients with inflammatory bowel disease. A successful bowel preparation that enables clear visualization of the intestinal mucosa is essential to diagnose and treat the underlying pathology. Currently, gastroenterologists use a variety of colon cleansing preparations, but Polyethylene Glycol (PEG) 3350 given for three to four days appears to be standard. Though it is well tolerated, safe and effective the duration of preparation may cause disruption to the routine and missed school days. To date, there is limited data that shows efficacy of a shorter duration of bowel preparation with PEG. This study aims to compare the efficacy and safety of a one-day preparation with that of a three-day preparation with PEG 3350 as preparation for colonoscopy in children and young adults.
Interventions
None listed
Sponsors
St. John Health System, Michigan
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to 21 Years
Healthy volunteers
Yes
Inclusion criteria
* Pediatric Patients referred for an outpatient colonoscopy
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Safety of a one day versus a three day colonoscopy preparation in a pediatric population | 02/08-06/10 (28 months) | The Safety of the different preparations was documented by monitoring serum electrolytes before and after the preparation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Tolerability of a one day versus a three day colonoscopy preparation in a pediatric population | 02/08-06/10 (28 months) | The tolerability was documented by monitoring the patient's clinical ability to consume the entire colonoscopy preparation without abdominal pain, nausea or vomiting. Furthermore, this was objectively documented by monitoring and recording the following parameters: Ease of Administration, Compliance, Willingness to take again |
Countries
United States
Outcome results
None listed